14491-41-9

Basic information

• Product Name: 1-chloro-4-(hept-1-yn-1-yl)benzene
• Synonyms: 1-chloro-4-(hept-1-yn-1-yl)benzene
• CAS NO: 14491-41-9
• Molecular Weight: 206.715
• Mol File: 14491-41-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1-chloro-4-(hept-1-yn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-(hept-1-yn-1-yl)benzene(14491-41-9)
• EPA Substance Registry System: 1-chloro-4-(hept-1-yn-1-yl)benzene(14491-41-9)

Safety Data

• Hazardous Substances Data: 14491-41-9(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 693-02-7 hex-1-yne 
• 19821-84-2 1-bromohept-1-yne 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 5663-96-7 oct-2-ynoic acid 
• 628-71-7 1-Heptyne 
• 106-46-7 para-dichlorobenzene 
• 106-39-8 bromochlorobenzene 

Relevant articles and documents

Synthesis of trisubstituted olefins via nickel-catalyzed decarboxylative hydroalkylation of internal alkynes

A novel NiH-catalyzed decarboxylative hydroalkylation of internal alkynes has been developed. Trisubstituted olefins were obtained in moderate to good yields with good regioselectivities. The reaction involves cis addition of NiH to the internal alkyne. The reaction shows good functional-group tolerance.

Synthesis of diarylalkynes by iron/copper co-catalyzed decarboxylative sp-sp2 coupling of alkynyl carboxylic acids and aryl halides

The highly effective decarboxylative sp-sp2 coupling of alkynylcarboxylic acids with various aryl halides was carried in the presence of low-cost and readily available copper(I) iodide/iron(III) acetylacetonate under ligand-free and palladium-free conditions using low catalyst loadings. This protocol makes such coupling reactions more practical and useful. Copyright

Copper-catalyzed cross-coupling of alkyl and aryl grignard reagents with alkynyl halides

(Chemical Equation Presented) Good old copperl A new general procedure to couple aliphatic and aromatic Grignard reagents with alkynyl halides under copper catalysis is described (see scheme; NMP=N-methylpyrrolidinone). The reaction is chemoselective and allows preparation of a vast array of simple and functionalized internal alkynes in high yields.