14491-44-2Relevant academic research and scientific papers
Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys
Ye, Qiuji,Chourey, Shishir,Reddy, Chintam Nagendra,Wang, Rui,Cossette, Chantal,Gravel, Sylvie,Slobodchikova, Irina,Vuckovic, Dajana,Rokach, Joshua,Powell, William S.
supporting information, p. 388 - 401 (2020/01/25)
Background and Purpose: The 5-lipoxygenase product 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE), acting through the OXE receptor, is a potent eosinophil chemoattractant that may be an important proinflammatory mediator in eosinophilic diseases su
2,2-Dichloroalkanecarboxylic acids, processes for their production and pharmaceutical agents containing these
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, (2008/06/13)
Pharmaceutical agents for treating diabetus mellitus which contain a compound of formula I STR1 as the active substance, in which A, B, A' and W have the meanings stated in the claims, new compounds of formula I as well as processes for their production.
ω-Substituted alkyl carboxylic acids as antidiabetic and lipid-lowering agents
Meyer, Kirstin,Voss, Edgar,Neidlein, Richard,Kuehnle, Hans-Frieder,Pill, Johannes
, p. 775 - 787 (2007/10/03)
In screening experiments certain ω-substituted alkyl carboxylic acids were found to produce an increase in insulin-stimulated 14C-acetate incorporation into triglycerides, which may indicate an improvement in the action of insulin. Antidiabetic
