161725-12-8

Basic information

• Product Name: 5-(4-chlorokphenyl)pentanoic acid
• Synonyms: 5-(4-chlorokphenyl)pentanoic acid
• CAS NO: 161725-12-8
• Molecular Formula: C₁₁H₁₃ClO₂
• Molecular Weight: 212.67272
• EINECS: -0
• Mol File: 161725-12-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-(4-chlorokphenyl)pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-chlorokphenyl)pentanoic acid(161725-12-8)
• EPA Substance Registry System: 5-(4-chlorokphenyl)pentanoic acid(161725-12-8)

Safety Data

• Hazardous Substances Data: 161725-12-8(Hazardous Substances Data)

Usage

Main properties

1. Chemical name: 5-(4-chlorokphenyl)pentanoic acid
2. Common name: Fenofibric acid
3. Medication type: Used to treat high cholesterol and triglyceride levels
4. Drug class: Fibrates
5. Dosage forms: Tablets and capsules for oral administration

Specific content

1. Mechanism of action: Reduces cholesterol production and improves removal from bloodstream
2. Use: Helps lower the risk of heart disease and other related conditions
3. Derivative of: Fenofibrate
4. Administration: Typically prescribed in combination with a healthy diet and exercise
5. Precautions: Consult healthcare professional for appropriate dosage and possible interactions with other medications

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 5724-02-7 5-(4-chlorophenyl)pent-4-enoic acid 
• 108-55-4 glutaric anhydride, 
• 36978-49-1 4-(4-chlorobenzoyl)butanoic acid 
• 71354-29-5 methyl 5-(4-chlorophenyl)-5-oxopentanoate 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 108-90-7 chlorobenzene 
• 124-38-9 carbon dioxide 
• 3047-24-3 4-(p-chlorophenyl)-1-butene 
• 75677-02-0 3-(4-chlorophenyl)propionaldehyde 
• 6282-88-8 3-(p-chlorophenyl)propanol 
• 371111-50-1 ethyl-5-(4-chlorophenyl)pent-2-enoate 
• 371111-51-2 5-(4-chloro-phenyl)-pentanoic acid ethyl ester 

Downstream Products

• 112607-05-3 δ-(p-chlorophenyl)-δ-valerolactone 
• 14469-86-4 1-Hydroxy-5-<4-chlor-phenyl>-pentan 
• 371110-93-9 (S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-oxa-10,13-diaza-tricyclo[17.2.2.1^3,7]tetracosa-1⁽²²⁾,3,5,7⁽²⁴⁾,19⁽²³⁾,20-hexaene-9-carbonyl)-amino]-2-oxo-hexanoylamino}-acetylamino)-phenyl-acetic acid tert-butyl ester 
• 371111-53-4 [12S,9S]-(2-{3-[(12-cyclohexyl-11,14-dioxo-2-oxa-10,13-diazatricyclo[17.2.2.1^3,7]tetracosa-1⁽²²⁾,3⁽²⁴⁾,4,6,19⁽²³⁾,20-hexaene-9-carbonyl)amino]-2-hydroxyhexanoylamino}acetylamino)-[S]-phenylacetic acid tert-butyl ester 
• 371111-52-3 methyl [12S,9S]-(12-cyclohexyl-11,14-dioxo-2-oxa-10,13-diazatricyclo[17.2.2.1^3,7]tetracosa-1⁽²²⁾,3⁽²⁴⁾,4,6,19⁽²³⁾,20-hexane-9-carboxylate) 

Relevant articles and documents

Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys

Background and Purpose: The 5-lipoxygenase product 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE), acting through the OXE receptor, is a potent eosinophil chemoattractant that may be an important proinflammatory mediator in eosinophilic diseases su

Combined Photoredox/Enzymatic C?H Benzylic Hydroxylations

Chemical transformations that install heteroatoms into C?H bonds are of significant interest because they streamline the construction of value-added small molecules. Direct C?H oxyfunctionalization, or the one step conversion of a C?H bond to a C?O bond, could be a highly enabling transformation due to the prevalence of the resulting enantioenriched alcohols in pharmaceuticals and natural products,. Here we report a single-flask photoredox/enzymatic process for direct C?H hydroxylation that proceeds with broad reactivity, chemoselectivity and enantioselectivity. This unified strategy advances general photoredox and enzymatic catalysis synergy and enables chemoenzymatic processes for powerful and selective oxidative transformations.

Iron-copper cooperative catalysis in the reactions of alkyl grignard reagents: Exchange reaction with alkenes and carbometalation of alkynes

Iron-copper cooperative catalysis is shown to be effective for an alkene-Grignard exchange reaction and alkylmagnesiation of alkynes. The Grignard exchange between terminal alkenes (RCH=CH2) and cyclopentylmagnesium bromide was catalyzed by FeCl3 (2.5 mol %) and CuBr (5 mol %) in combination with PBu3 (10 mol %) to give RCH2CH 2MgBr in high yields. 1-Alkyl Grignard reagents add to alkynes in the presence of a catalyst system consisting of Fe(acac)3, CuBr, PBu3, and N,N,N″,N″-tetramethylethylenediamine to give β-alkylvinyl Grignard reagents. The exchange reaction and carbometalation take place on iron, whereas copper assists with the exchange of organic groups between organoiron and organomagnesium species through transmetalation with these species. Sequential reactions consisting of the alkene-Grignard exchange and the alkylmagnesiation of alkynes were successfully conducted by adding an alkyne to a mixture of the first reaction. Isomerization of Grignard reagents from 2-alkyl to 1-alkyl catalyzed by Fe-Cu also is applicable as the first 1-alkyl Grignard formation step.