1449134-85-3

Upstream product

• 98-88-4 benzoyl chloride 
• 32566-01-1 2-(2-aminophenyl)-1H-indole 
• 58995-87-2 N-[2-(1H-indol-2-yl)phenyl]benzamide 
• 1449134-97-7 N-(2-(1-acetyl-1H-indol-2-yl)phenyl)benzamide 

Downstream Products

• 1449135-19-6 (2'R,3'R)-1'-acetyl-2-phenylspiro[benzo[d][1,3]oxazine-4,2'-indolin]-3'-yl nitrate 
• 1449135-20-9 1-((2'R)-3'-hydroxy-2-phenylspiro[benzo[d][1,3]oxazine-4,2'-indolin]-1'-yl)ethanone 

Relevant academic research and scientific papers

Enantioselective chlorocyclization of indole derived benzamides for the synthesis of spiro-indolines

(DHQD)2PHAL catalyzed enantioselective chlorocyclization of indole derived benzamides was realized. Spiro-indolines containing a continuous quaternary carbon center and tertiary carbon center were obtained in good yields with excellent enantioselectivity (up to 90% yield and 96% ee).