144918-22-9

Upstream product

• 144918-21-8 ethyl 2-bromo-3-(3,4-dimethoxyphenyl)-3-(prop-2-ynyloxy)propanoate 
• 20583-78-2 ethyl (E)-3,4-dimethoxycinnamate 
• 20583-78-2 3,4-dimethoxy-cinnamic acid ethyl ester 

Downstream Products

• 144918-23-0 2-(3,4-dimethoxyphenyl)-3-(hydroxymethyl)-4-methylenetetrahydrofuran 
• 144918-25-2 (4S,5R)-4-(3,4-Dimethoxy-benzyloxymethyl)-5-(3,4-dimethoxy-phenyl)-dihydro-furan-3-one 
• 144918-24-1 (2R,3S)-3-(3,4-Dimethoxy-benzyloxymethyl)-2-(3,4-dimethoxy-phenyl)-4-methylene-tetrahydro-furan 
• 469-28-3 (+/-)-Isogmelinol 

Relevant academic research and scientific papers

Titanocene(III) mediated radical cyclization of α-bromo carbonyl compounds: Synthesis of tri-substituted tetrahydrofurans

A novel and efficient methodology has been developed for the construction of synthetically important tri-substituted tetrahydrofuran derivatives from bromo-alkenes and bromo-alkynes by radical cyclization reactions using the radical initiator Cp2/su

Indium(I) iodide as a radical initiator: Intramolecular cyclization of functionalized bromo-alkynes to substituted tetrahydrofurans

Aryl substituted α-carbonyl bromo-alkynes undergo facile cyclizations to the corresponding substituted 4-methylene-tetrahydrofurans using indium(I) iodide in acetonitrile under sonication in high yields. The reaction is predicted to proceed via a radical

Synthesis and structural aspects of some intermediates in furofuran lignan synthesis

The synthesis of some intermediates of furofuran lignans was accomplished by a chemical cyclisation reaction using N-ethylpiperidine hypophosphite and azobisisobutyronitrile. This reaction afforded the 5-exo-dig cyclic compound as the major product along

Stereoselective synthesis of trisubstituted tetrahydrofurans by radical cyclisation reaction using a hypophosphite salt. Application to the total synthesis of (±)-dihydrosesamin

The stereoselective synthesis of tetrahydrofurans has been achieved from bromoalkynes and bromoalkenes by intramolecular radical cyclisation using a hypophosphite salt. This radical cyclisation strategy has successfully been applied to the total synthesis

Stereoselective Total Synthesis of (+/-)-Paulownin and (+/-)-Isogmelinol through Radical Annulation Route

A highly stereocontrolled synthesis of furofuran lignans, (+/-)-Paulownin (1a) and (+/-)-Isogmelinol (1b) is described involving intramolecular radical cyclisation as a key step.

Stereoselective Radical Annulation Route to the Synthesis of (+/-)-Paulownin und (+/-)-Isogmelinol

A highly stereocontrolled synthesis of (+/-)-Paulownin (1a) and (+/-)-isogmelinol (1b) is reported involving intramolecular radical cyclisation reaction as a key step.