1449291-35-3Relevant academic research and scientific papers
Kinetic resolution of tertiary alcohols: Highly enantioselective access to 3-hydroxy-3-substituted oxindoles
Lu, Shenci,Poh, Si Bei,Siau, Woon-Yew,Zhao, Yu
supporting information, p. 1731 - 1734 (2013/04/10)
Enantioselective: The first highly enantioselective kinetic resolution of 3-hydroxy-3-substituted oxindoles has been developed through oxidative esterification catalyzed by a N-heterocyclic carbene (see picture). This method uses a simple procedure and provides 3-hydroxy-oxindoles with various substituents at the 3-position in excellent enantiopurity. S=selectivity. Copyright
