1449331-33-2

Upstream product

• 3264-21-9 1-acetylpyrene 
• 1449331-28-5 benzyl 2-oxo-2-(pyren-1-yl)ethyl carbonate 
• 1449331-29-6 2-isopropyl-5-methylcyclohexyl 2-oxo-2-(pyren-1-yl)ethyl carbonate 
• 1449331-30-9 (8R,9R,10S,13S,14R,17S)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-10,13-dimethyl-17-((S)-6-methylheptan-2-yl)-1H-cyclopenta[a]phenanthren-3-yl 2-oxo-2-(pyren-1-yl)ethyl carbonate 
• 1449331-31-0 2-oxo-2-(pyren-1-yl)ethyl phenyl carbonate 
• 1192592-19-0 2-hydroxy-1-(pyren-1-yl)ethanone 
• 7693-46-1 4-Nitrophenyl chloroformate 
• 80480-15-5 1-(bromoacetyl)pyrene 

Relevant academic research and scientific papers

1-(Hydroxyacetyl)pyrene a new fluorescent phototrigger for cell imaging and caging of alcohols, phenol and adenosine

1-(Hydroxyacetyl)pyrene has been introduced as a new fluorescent phototrigger for alcohols and phenols. Alcohols and phenols were protected as their corresponding carbonate esters by coupling with fluorescent phototrigger, 1-(hydroxyacetyl)pyrene. Photophysical studies of caged carbonates showed that they all exhibited strong fluorescence properties. Irradiation of the caged carbonates by visible light (≥410 nm) in aqueous acetonitrile released the corresponding alcohols or phenols in high chemical (95-97%) and quantum (0.17-0.21) yields. The mechanism for the photorelease was proposed based on Stern-Volmer quenching experiments and solvent effect studies. Importantly, 1-(hydroxyacetyl)pyrene showed as a phototrigger for rapid photorelease of the biologically active molecule adenosine. In vitro biological studies revealed that 1-(hydroxyacetyl)pyrene has good biocompatibility, cellular uptake property and cell imaging ability. The Royal Society of Chemistry and Owner Societies 2012.