1449336-19-9

Basic information

• Product Name: benzyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate
• Synonyms: benzyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate
• CAS NO: 1449336-19-9
• Molecular Weight: 284.268
• Mol File: 1449336-19-9.mol

Chemical Properties

• CAS DataBase Reference: benzyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate(1449336-19-9)
• EPA Substance Registry System: benzyl 2-(benzo[d][1,3]dioxol-5-yl)-2-oxoacetate(1449336-19-9)

Safety Data

• Hazardous Substances Data: 1449336-19-9(Hazardous Substances Data)

Upstream product

• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 7579-36-4 dibenzyl oxalate 
• 62396-98-9 benzo[1,3]dioxol-5-yl-oxo-acetic acid 
• 100-39-0 benzyl bromide 
• 538-60-3 dibenzyl hydrogen phosphite 
• 65709-23-1 3,4-methylenedioxyphenylglyoxal 

Downstream Products

• 1449336-13-3 C₂₃H₁₉NO₆S 
• 1449335-94-7 C₂₉H₂₇NO₈S 
• 1449336-10-0 C₂₉H₂₇NO₈S 

Relevant articles and documents

2-Oxo promoted hydrophosphonylation & aerobic intramolecular nucleophilic displacement reaction

Highly efficient catalyst free methods for the synthesis of α-hydroxy-β-oxophosphonates and α-oxoesters have been described. The existence of a 2-oxo group in α-oxoaldehydes is a key factor in promoting the reaction of the tervalent phosphite form towards 2-oxoaldehydes in the synthesis of α-hydroxy-β-oxophosphonates. The in situ activated α-C-H atom of α-hydroxy-β-oxophosphonates sustains aerobic intramolecular nucleophilic displacement in a curious way to produce α-oxoester.

Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of α-Iminoesters

An efficient Pd(OAc)2-catalyzed asymmetric hydrogenation of α-iminoesters was realized for the first time at 1 atm hydrogen pressure and room temperature. Pd(OAc)2, a less expensive Pd salt with low toxicity, was found to be the most suitable catalyst precursor rather than Pd(TFA)2 which is usually the catalyst of choice for homogeneous asymmetric hydrogenation. The chiral α-arylglycine fragments are widely found in many chiral products and bioactive molecules.

Organocatalyzed formal [2 + 2] cycloaddition of ketimines with allenoates: Facile access to azetidines with a chiral tetrasubstituted carbon stereogenic center

An enantioselective organocatalyzed aza-MBH-type reaction of ketimines and allenoates has been developed. The present formal [2 + 2] cycloaddition produces highly functionalized azetidines with a chiral tetrasubstituted carbon stereogenic center in good to excellent yields and high enantioselectivities.