1449414-87-2Relevant academic research and scientific papers
Decarboxylative acylation of arenes with mandelic acid derivatives via palladium-catalyzed oxidative sp2 C-H activation
Liu, Xia,Yi, Ze,Wang, Jianhui,Liu, Guiyan
, p. 10641 - 10646 (2015)
An efficient palladium catalyzed decarboxylative acylation of arenes with mandelic acid derivatives via oxidative sp2 C-H activation in the presence of tert-butyl hydroperoxide has been developed. The acylation reaction is assisted by a pyridine directing group. The starting materials are inexpensive and readily available. This method provides an economical and convenient way to synthesize aryl ketones.
Arylmethyl chlorides: New bifunctional reagents for palladium-catalyzed ortho -chlorination and acylation of 2-arylpyridines
Zhang, Guodong,Sun, Suyan,Yang, Fan,Zhang, Qian,Kang, Jianxun,Wu, Yusheng,Wu, Yangjie
, p. 443 - 450 (2015/02/19)
A chemoselective, palladium-catalyzed, ligand-directed ortho-C-H chlorination and acylation process has been developed, exhibiting high regioselectivity for 2-arylpyridines bearing a meta-substituent. Worthy of note is the fact that arylmethyl chlorides a
Palladium catalyzed direct ortho C-H acylation of 2-arylpyridines using toluene derivatives as acylation reagents
Xu, Zhipeng,Xiang, Biao,Sun, Peipei
, p. 1679 - 1682 (2013/03/13)
A facile ortho-acylation of 2-arylpyridines by a Pd-catalyzed oxidative C-H activation was developed, in which no prefunctionalized toluene derivatives were used as acylation reagents in a tandem reaction to form 2-pyridyldiaryl ketones with moderate yiel
