144942-89-2 Usage
Description
Amino-PEG1-acid is a PEG linker containing an amino group (NH2) with a terminal carboxylic acid (CO2H). NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC , or directly with NHS esters, to form a stable amide bond.
Check Digit Verification of cas no
The CAS Registry Mumber 144942-89-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,9,4 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144942-89:
(8*1)+(7*4)+(6*4)+(5*9)+(4*4)+(3*2)+(2*8)+(1*9)=152
152 % 10 = 2
So 144942-89-2 is a valid CAS Registry Number.
144942-89-2Relevant articles and documents
Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery
-
Paragraph 0170, (2015/10/28)
The present invention is directed membrane active poly(vinyl ester) polymers and compositions for targeted delivery of RNA interference (RNAi) polynucleotides to cells in vivo. RNAi polynucleotides are conjugated to the poly(vinyl ester) polymers and the polymers are reversibly modified to enable in vivo targeted delivery. Membrane activity of the poly(vinyl ester) provides for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness.
