1449488-39-4Relevant academic research and scientific papers
Metal-Free Mediated C-3 Methylsulfanylation of Imidazo[1,2- a ]-pyridines with Dimethyl Sulfoxide as a Methylsulfanylating Agent
Chen, Zhengkai,Cao, Gangjian,Zhang, Fengjin,Li, Hongli,Xu, Jianfeng,Miao, Maozhong,Ren, Hongjun
, p. 1795 - 1800 (2017)
A simple approach is described for the regioselective C-3 methylsulfanylation of imidazo[1,2- a ]pyridines through diiodine-mediated, acetone-promoted, C-S bond construction with dimethyl sulfoxide as both the source of the methylsulfanyl moiety and the s
DMSO-POCl3: A reagent for methylthiolation of imidazo[1,2-a]pyridines and other imidazo-fused heterocycles
Patil, Shashikant M.,Kulkarni, Sarang,Mascarenhas, Malcolm,Sharma, Rajiv,Roopan, S. Mohana,Roychowdhury, Abhijit
, p. 8255 - 8262 (2013/09/02)
A practical and metal free method for methylthiolation of imidazo[1,2-a]pyridines and other imidazo-fused heterocycles using DMSO-POCl3 complex is reported. The reactions are carried out at room temperature that give the corresponding methylthiolated products in good to excellent yield. Further, its application to indole has been demonstrated.
