1449488-53-2Relevant academic research and scientific papers
Regioselective oxidative cross-coupling of benzo[d] imidazo[2,1- b] thiazoles with styrenes: A novel route to C3-dicarbonylation
Shaik, Siddiq Pasha,Sultana, Faria,Ravikumar,Sunkari, Satish,Alarifi, Abdullah,Kamal, Ahmed
, p. 7696 - 7704 (2017/09/27)
A novel I2 promoted, highly efficient metal-free and peroxide-free greener domino protocol for the C3-dicarbonylation of benzo[d]imidazo[2,1-b]thiazoles (IBTs) with styrenes has been developed via oxidative cleavage of the C(sp2)-H bond, followed by C3-nucleophilic attack of IBT and oxidation. Interestingly, under these conditions 2-(benzo[d]imidazo[2,1-b]thiazol-2-yl)aniline gave the benzo[4′,5′]thiazolo[2′,3′:2,3]imidazo[4,5-c]quinoline derivative via oxidative cleavage of the C(sp2)-H bond, followed by Pictet-Spengler cyclization and aromatization. This method offers the advantages of broad substrate scope, ecofriendly feature and high atom economy apart from higher yields.
Metal-Free Mediated C-3 Methylsulfanylation of Imidazo[1,2- a ]-pyridines with Dimethyl Sulfoxide as a Methylsulfanylating Agent
Chen, Zhengkai,Cao, Gangjian,Zhang, Fengjin,Li, Hongli,Xu, Jianfeng,Miao, Maozhong,Ren, Hongjun
supporting information, p. 1795 - 1800 (2017/09/30)
A simple approach is described for the regioselective C-3 methylsulfanylation of imidazo[1,2- a ]pyridines through diiodine-mediated, acetone-promoted, C-S bond construction with dimethyl sulfoxide as both the source of the methylsulfanyl moiety and the s
DMSO-POCl3: A reagent for methylthiolation of imidazo[1,2-a]pyridines and other imidazo-fused heterocycles
Patil, Shashikant M.,Kulkarni, Sarang,Mascarenhas, Malcolm,Sharma, Rajiv,Roopan, S. Mohana,Roychowdhury, Abhijit
, p. 8255 - 8262 (2013/09/02)
A practical and metal free method for methylthiolation of imidazo[1,2-a]pyridines and other imidazo-fused heterocycles using DMSO-POCl3 complex is reported. The reactions are carried out at room temperature that give the corresponding methylthiolated products in good to excellent yield. Further, its application to indole has been demonstrated.
