1449493-52-0Relevant articles and documents
Facile synthesis of guaiazulene-heterocycle hybrids via multicomponent reactions involving formation of zwitterionic intermediates
Sato, Koichi,Yokoo, Erina,Takenaga, Naoko
, p. 807 - 814 (2013/05/08)
The synthesis of a series of guaiazulene-heterocycle hybrids via zwitterionic intermediates was performed. The multicomponent reactions of 3-isocyano-7-isopropyl-1,4-dimethylazulene 1, dimethyl acetylenedicarboxylate 2, and a third reactant 3 (cyclic CH-acids, phenols, aldehydes or amines) proceeded to afford heterocyclic guaiazulene derivatives 4.