144950-26-5Relevant articles and documents
The synthesis and biological activity of certain 4'-thionucleosides
Secrist III,Parker,Tiwari,Messini,Shaddix,Rose,Bennett Jr.,Montgomery
, p. 675 - 686 (2007/10/02)
Results are presented on the synthesis and biological activity of several types of 4'-thionucleosides as potential anticancer agents. Detailed studies on the mechanism of action of 4'-thiothymidine are also presented.
Synthesis and biological activity of 4'-thionucleosides of 2- chloroadenine
Tiwari,Secrist III,Montgomery
, p. 1819 - 1828 (2007/10/02)
1,2,3,5-Tetra-O-acetyl-4-thio-D-ribofuranose, prepared from 2,3,5-tri-O- benzyl-D-ribofuranose in four steps, was converted to the corresponding 2- chloroadenine nucleoside (8), which was deoxygenated to obtain 2-chloro-2'- deoxy-4'-thioadenosine (12). Th