1449588-84-4

Upstream product

• 123558-64-5 N-(4-methoxybenzyl)-2,2,2-trichloroacetamide 
• 160238-45-9 (2S)-3-(4-methoxybenzyloxy)-2-methyl-1-propanol 
• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 1449588-75-3 (2S,3S)-2-(methoxymethoxy)-3-methylpent-4-en-1-ol 
• 1449588-74-2 (S)-5-((S)-but-3-en-2-yl)-8,8,9,9-tetramethyl-2,4,7-trioxa-8-siladecane 
• 1449588-78-6 (2S,5S,6S)-1-((4-methoxybenzyl)oxy)-5-(methoxymethoxy)-2,6-dimethyloct-7-en-4-ol 
• 1449588-76-4 (2S,3S)-2-(methoxymethoxy)-3-methylpent-4-enal 
• 479196-36-6 (2S,3S)-1-((tert-butyldimethylsilyl)oxy)-3-methylpent-4-en-2-ol 
• 220018-27-9 (R)-1-((3-bromo-2-methylpropoxy)methyl)-4-methoxybenzene 

Relevant academic research and scientific papers

Synthesis of an advanced intermediate of the jatrophane diterpene Pl-4: A dibromide coupling approach

The preparation of an advanced intermediate toward the synthesis of the jatrophane diterpene Pl-4 is described. The key step is a regioselective chelation-controlled lithiation of the (Z)-configured bromide in the corresponding vinyl dibromide precursor. The method outlined within this Article is suitable for the facile access of sterically hindered internal vinyl halides for further coupling reactions.