1449680-57-2Relevant academic research and scientific papers
The iron-catalyzed construction of 2-aminopyrimidines from alkynenitriles and cyanamides
Lane, Timothy K.,Nguyen, Minh H.,D'Souza, Brendan R.,Spahn, Nathan A.,Louie, Janis
supporting information, p. 7735 - 7737 (2013/09/02)
Several cycloaddition catalysts and reagents were surveyed for their effectiveness toward cyclizing alkynenitriles with cyanamides. Catalytic amounts of FeI2, iPrPDAI and Zn were found to effectively catalyze the [2+2+2] cycloaddition of a variety of cyanamides and alkynenitriles to afford bicyclic 2-aminopyrimidines.
