1449685-41-9Relevant academic research and scientific papers
C-H functionalization of cyclopropanes: A practical approach employing a picolinamide auxiliary
Roman, Daniela Sustac,Charette, Andre B.
, p. 4394 - 4397 (2013)
A Pd-catalyzed, picolinamide-enabled, and efficient C-H arylation of cyclopropanes is described. The reaction can be promoted by either a silver additive or catalytic pivalic acid in the presence of a carbonate base. Various aryl iodides can be employed as coupling partners, providing exclusively cis-substituted cyclopropylpicolinamides.
