144970-91-2Relevant academic research and scientific papers
Phenylsulfenyl D-Ribofuranosides as Efficient Ribosyl Donors: Application to the Synthesis of -(Deoxy)Nucleosides
Chanteloup, Luc,Beau, Jean-Marie
, p. 5347 - 5350 (2007/10/02)
Readily available phenylsulfenyl 2,3,5-tri-O-benzoyl-β-D-ribofuranoside glycosylates silylated nucleobases in a fast, high-yielding and stereoselective reaction promoted by trimethylsilyl trifluoromethanesulfonate.The method has been applied to the synthesis of labelled nucleosides further transformed to building blocks ready for oligodeoxynucleotide construction. Key words: anomeric sulfoxides; silylated nucleobases; nucleosides; 2'-deoxynucleosides.
