1449701-55-6

Basic information

• Product Name: (E)-1-benzylidene-N-(2-fluorophenyl)-1H-indene-3-carboxamide
• Synonyms: (E)-1-benzylidene-N-(2-fluorophenyl)-1H-indene-3-carboxamide
• CAS NO: 1449701-55-6
• Molecular Weight: 341.385
• Mol File: 1449701-55-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-1-benzylidene-N-(2-fluorophenyl)-1H-indene-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-benzylidene-N-(2-fluorophenyl)-1H-indene-3-carboxamide(1449701-55-6)
• EPA Substance Registry System: (E)-1-benzylidene-N-(2-fluorophenyl)-1H-indene-3-carboxamide(1449701-55-6)

Safety Data

• Hazardous Substances Data: 1449701-55-6(Hazardous Substances Data)

Upstream product

• 135-19-3 β-naphthol 
• 348-54-9 2-Fluoroaniline 
• 100-52-7 benzaldehyde 
• 773-90-0 1-diazo-2(1H)naphthalenone 

Relevant articles and documents

Efficient synthesis of indene derivatives by cascade reactions

The present invention relates to an efficient synthesis method of indene derivatives through cascade reaction. In the present invention, a novel one-pot cascade approach to the synthesis of 1H-indene-3-carboxamides and 1H-indene-3-carboxylate derivatives through thermolysis of a diazo compound is developed. Along with various aromatic and heteroaromatic aldehydes, aliphatic or aromatic primary amine and aliphatic alcohol or phenol derivative are used as nucleophilic components. In the present invention, a multicomponent reaction without using a catalyst enables the synthesis of variously functionalized indene derivatives, and can be widely applied to the synthesis of natural products and medicine.