1449753-71-2Relevant academic research and scientific papers
Preparation of (Z)-α,β-disubstituted enamides via palladium-catalyzed addition of boronic acids to ynamides
Yang, Yuanfa,Wang, Lina,Zhang, Fang,Zhu, Gangguo
, p. 9319 - 9324 (2014)
A Pd-catalyzed, highly regio- and stereoselective addition of boronic acids to ynamides has been realized. This protocol generates (Z)-α,β-disubstituted enamides in high yields with excellent regio- and stereoselectivity under the mild reaction conditions, thereby providing a good complementary method for the diverse synthesis of multifunctional enamides. A wide collection of functional groups are found to be tolerated. It represents a straightforward and useful means to assemble stereodefined enamides from readily available starting materials.
Arylations of substituted enamides by aryl iodides: Regio- and stereoselective synthesis of (z)-β-amido-β-arylacrylates
Gou, Quan,Deng, Bin,Zhang, Hongbin,Qin, Jun
supporting information, p. 4604 - 4607 (2013/09/24)
Arylations of substituted enamides by aryl iodides were achieved for the first time via an unusual PdCl2(COD)/Ag3PO4 catalytic system. A broad range of (Z)-β-amido-β-arylacrylates were prepared regio- and stereoselectively in a highly efficient manner.
