683246-77-7

Basic information

• Product Name: 2-Pyrrolidinone, 1-(phenylethynyl)-
• CAS NO: 683246-77-7
• Molecular Formula: C12H11NO
• Molecular Weight: 185.225
• Mol File: 683246-77-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: 49-50 °C
• Boiling Point: 301.7±25.0 °C(Predicted)
• Density: 1.18±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-Pyrrolidinone, 1-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 1-(phenylethynyl)-(683246-77-7)
• EPA Substance Registry System: 2-Pyrrolidinone, 1-(phenylethynyl)-(683246-77-7)

Safety Data

• Hazardous Substances Data: 683246-77-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 536-74-3 phenylacetylene 
• 616-45-5 2-pyrrolidinon 
• 7436-90-0 2,2-dibromostyrene 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 13146-23-1 copper(I) phenylacetylenide 

Downstream Products

• 1174638-28-8 2,2-di(2-oxo-pyrrolidin-1-yl)-vinylbenzene 
• 1422721-63-8 (E)-1-(1-bromo-2-phenylvinyl)pyrrolidin-2-one 
• 3287-02-3 4-(phenylethynyl)toluene 
• 1375415-59-0 1-((E)-1-fluoro-2-phenylvinyl)pyrrolidin-2-one 
• 1280737-92-9 (E)-diethyl 2-(2-oxopyrrolidin-1-yl)-1-phenylvinylphosphonate 
• 1245223-42-0 1-[(E)-2-(4-acetylphenyl)-2-phenylvinyl]pyrrolidin-2-one 
• 1190789-29-7 (Z)-6-(2-oxopyrrolidin-1-yl)-5-phenylhex-5-enoic acid ethyl ester 
• 19883-35-3 (Z)-N-(2-phenylethenyl)-2-pyrrolidinone 
• 1134172-61-4 1-[(E)-2-phenyl-2-thiophen-2-ylvinyl]pyrrolidin-2-one 
• 1134172-52-3 3-[(Z)-2-phenylhex-1-enyl]pyrrolidin-2-one 
• 127978-78-3 1-(2-oxopyrrolidin-1-yl)-2-phenylethane-1,2-dione 
• 1449753-71-2 (Z)-1-(1,2-diphenylvinyl)pyrrolidin-2-one 

Relevant articles and documents

Visible-Light-Promoted Oxo-Sulfonylation of Ynamides with Sulfonic Acids

A visible-light-promoted oxo-sulfonylation of ynamides with sulfonic acids is reported, giving rise to a collection of functionalized α-sulfonylated amides in a straightforward manner. The reaction proceeds sequentially through a cascade of electrophilic addition and photoinduced sulfonyl radical-sustained skeleton rearrangement. The high atom economy, mild reaction conditions, and wide substrate scope comprised the merits of this synthetic transformation.

Iridium-Catalyzed Highly Regioselective Azide-Ynamide Cycloaddition to Access 5-Amido Fully Substituted 1,2,3-Triazoles under Mild, Air, Aqueous, and Bioorthogonal Conditions

A highly regioselective method to access 5-amido fully substituted 1,2,3-triazoles by iridium-catalyzed azide-ynamide cycloaddition under mild, air, aqueous, and bioorthogonal conditions is reported. The excellent regioselectivities may derive from the strong coordination between the carbonyl oxygen of ynamide and the -acidic iridium. Since the iridium ion is insensitive to oxygen/water and exhibits low cytotoxicity, it could catalyze this reaction in both organic and biological environments efficiently. Preparation in gram-scale and application in carbohydrates highlight this method.

Addition of selenium(II) bromide to arylalkynylamides - a route to hypervalent T-shaped 10-Se-3 systems

Abstract A route for the generation of hypervalent T-shaped 10-Se-3 systems is described involving an interaction between in situ prepared selenium(II) bromide and an aryl alkynyl amide derivative. The existence of hypervalent selenium in both the solid and solution states has been supported by X-ray analysis and 77Se NMR data.