144987-02-0Relevant articles and documents
A new route to functionalized 3-aminopyridazines by ANRORC type ring transformation of 1,2,4-triazines with carbon nucleophiles [1]
Rykowski,Wolinska,Van Der Plas
, p. 879 - 883 (2000)
The reaction of 3-chloro-6-phenyl-1,2,4-triazine 1a with carbon nucleophiles 2a-d bearing a cyano substituent at a carbanionic center has been studied. In all reactions the formation of the corresponding 3-aminopyridazines 3a-d takes place via ANRORC mech
METAL COMPLEX, AND METHOD FOR SYNTHESIS OF NITROGEN-CONTAINING ORGANIC COMPOUND USING METAL COMPLEX
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Paragraph 0098-0099, (2017/04/29)
PROBLEM TO BE SOLVED: To provide a method that synthesizes a nitrogen-containing organic compound under a relatively mild condition and in a relatively simple process. SOLUTION: A method that synthesizes a nitrile compound includes a step for the reaction between an acid chloride and a complex represented by formula (1A) or formula (1B) (M1-M7 independently represent Ti, Zr, Hf, V, or the like; L1-L7 independently represent a ligand comprising a substituted/unsubstituted cyclopentadienyl derivative, a diphenylamine ligand or the like). SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
Synthesis of 13C, 15N-Enriched α-Dicarbonyl Model Adducts to Determine the Utility of 13Cand 15N NMR for Studying Mechanism-Based Inactivation of Cytochromes P-450 by Substituted Dichloroacetamides
Weiner, Scott J.,Holl, Susan M.,Covey, Douglas F.
, p. 122 - 127 (2007/10/02)
To determine the feasibility of using NMR to study the inactivation of cytochromes P-450 by dichloroacetamide-containing mechanism-based inactivators, 13C,15N-enriched compounds were synthesized, modeling adducts between the nucleophilic side-chain of cys