14505-80-7

Basic information

• Product Name: cis-2,6-dimethyloxan-4-one
• Synonyms: cis-2,6-dimethyloxan-4-one;CIS-2,6-DIMETHYLDIHYDRO-2H-PYRAN-4(3H)-ONE
• CAS NO: 14505-80-7
• Molecular Formula: C7H12O2
• Molecular Weight: 128.16898
• Mol File: 14505-80-7.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 50 °C(Press: 9.0 Torr)
• Appearance: /
• Density: 0.956±0.06 g/cm3(Predicted)
• CAS DataBase Reference: cis-2,6-dimethyloxan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: cis-2,6-dimethyloxan-4-one(14505-80-7)
• EPA Substance Registry System: cis-2,6-dimethyloxan-4-one(14505-80-7)

Safety Data

• Hazardous Substances Data: 14505-80-7(Hazardous Substances Data)

Usage

General Description

Cis-2,6-dimethyloxan-4-one is an organic chemical compound with the molecular formula C6H10O2. It is a cyclic ketone and is commonly used as a flavoring agent in the food industry, providing a sweet, fruity aroma. It can be found naturally in various fruits and is also used in the production of fragrances and other aromatic products. The cis isomer of 2,6-dimethyloxan-4-one has a specific spatial arrangement of its atoms, leading to distinct chemical and physical properties compared to the trans isomer. It is important to note that while cis-2,6-dimethyloxan-4-one is generally recognized as safe for use in food, it should still be handled and utilized with proper safety measures and guidelines.

Upstream product

• 1004-36-0 2,6-dimethylpyrone 
• 869293-25-4 (R)-5-((tert-butyldimethylsilyl)oxy)hex-1-en-3-one 
• 190912-17-5 (R)-2-methyl-2,3-dihydro-4H-pyran-4-one 
• 676-58-4 methylmagnesium chloride 
• 1393537-60-4 (E)-5-((R)-tert-butyldimethylsilyloxy)-1-(piperidin-1-ylimino)hexan-3-one 
• 917-54-4 methyllithium 
• 19185-89-8 2-methyl-2,3-dihydro-4H-pyran-4-one 
• 165876-14-2 (2S,6S)-2,6-dimethyl-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 155206-70-5 (4E)-4-Ethoxyhepta-4,6-dien-2-ol 
• 60-29-7 diethyl ether 
• 41866-70-0 2,6-dimethyl-4-hydroxy-2,3,5,6-tetrahydro-4H-pyran 
• 33747-09-0 (2R,4S,6S)-2,6-dimethyltetrahydro-2H-pyran-4-ol 
• 122222-69-9 5-t-butoxycarbonyl-2,6-dimethyl-2,3-dihydro-4H-pyran-4-one 
• 64-17-5 ethanol 

Downstream Products

• 1620450-76-1 C₁₈H₂₃NO₅ 
• 1620545-73-4 C₁₈H₂₃NO₅ 
• 928156-61-0 2-(trans-2,6-dimethyltetrahydro-2H-pyran-4-yl)acetic acid 
• 928156-60-9 2-((2R,6S)-2,6-dimethyltetrahydro-2H-pyran-4-yl)acetic acid 
• 41823-04-5 4-Ethinyl-2,6-dimethyl-tetrahydropyranol-4 

Relevant articles and documents

Enantiospecific Synthesis of (+)-(2R)- and (-)-(2S)-6-Ethyl-3,4-dihydro-2-methyl-4-oxo-2H-pyran-5-carboxylic Acid

The two enantiomers (-)-(2S)- and (+)-(2R)-6-ethyl-3,4-dihydro-2-methyl-4-oxo-2H-pyran-5-carboxylic acid ((S)- and (R)-7) have been synthesized from (+)-(3S) and (-)-(3R)-3-hydroxybutanoates, respectively (Scheme 1).By reduction and decarboxylation, the tetrahydro-2H-pyranols (2R,4R,6S)- and (2S,4S,6R)-13, respectively, were obtained with an enantiomeric excess of >/= 93 percent.

INHIBITOR OF BTK AND MUTANTS THEREOF

The disclosure includes compounds of Formula (I) (1) wherein Q0, Q1, Q2, Q3, Q4, Z, W, i, j, m, n, Warhead, R0, R1, R3, R4, R5, R6, and R7, are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.

HYDROXYL PURINE COMPOUNDS AND USE THEREOF

Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNFα inhibitors, in particular, the compounds as shown in formula (I), or tautomers or pharmaceutically acceptable salts thereof.