145057-90-5Relevant articles and documents
Exploring reversible reactions between CO2 and amines
Hampe, Erin M.,Rudkevich, Dmitry M.
, p. 9619 - 9625 (2007/10/03)
The 'old' chemistry between CO2 and primary alkylamines has been revisited. Amines 1 and 2, with appended aromatic fluorophores, reversibly reacted with CO2 in polar aprotic solvent (e.g. DMSO, DMF) with the formation of carbamic acids 3 and 4. As a result, strong fluorescence occurred, thus directly reporting on the CO2 entrapment. Carbamic acids were studied by 1H and 13C NMR spectroscopy in DMSO-d 6. The carbamate bond, despite being covalent, is reversible and can be broken upon heating or simply flashing solutions with inert gases. Synthesis and evaluation of a CO2-sensing amino acid-α-naphthylglycine 7 is also reported for potential CO2 monitoring under biorelevant conditions in aqueous solutions.
An Efficient and Practical Synthesis of L-α-Amino Acids Using (R)-Phenylglycinol as a Chiral Auxiliary
Inaba, Takashi,Kozono, Ichiro,Fujita, Makoto,Ogura, Katsuyuki
, p. 2359 - 2365 (2007/10/02)
L-α-Amino acids including L-α-arylglycines were conveniently and stereoselectively synthesized via the α-amino carbonitriles given by the Strecker reaction of (R)-2-amino-2-phenylethanol with aldehydes and hydrogen cyanide.The stereoselectivity of these α-amino carbonitriles was thermodynamically controlled.
