1450622-75-9

Upstream product

• 84892-37-5 4-(2-methoxyethyl)-1,1'-biphenyl 
• 931-51-1 cyclohexylmagnesiumchloride 
• 37729-18-3 2-(biphenyl-4-yl)ethanol 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 2350-89-2 p-vinylbiphenyl 
• 4441-56-9 cyclohexylboronic acid 
• 30166-77-9 (E)‐4‐(2-(phenylsulfonyl)vinyl)-1,1'-biphenyl 

Relevant academic research and scientific papers

Visible-Light-Mediated Alkenylation of Alkyl Boronic Acids without an External Lewis Base as an Activator

Herein we report a protocol for the direct visible-light-mediated alkenylation of alkyl boronic acids at room temperature without an external Lewis base as an activator, and we propose a mechanism involving benzenesulfinate activation of the alkyl boronic acids. The protocol permits the efficient functionalization of a broad range of cyclic and acyclic primary and secondary alkyl boronic acids with various alkenyl sulfones. We demonstrated its utility by preparing or functionalizing several pharmaceuticals and natural products.

Fe-promoted cross coupling of homobenzylic methyl ethers with Grignard reagents via sp3 C-O bond cleavage

The first iron-catalyzed formal cross coupling of homobenzylic methyl ethers with alkyl Grignard reagents is realized. The reaction is proposed to proceed through a sequence of dehydroalkoxylation to form the vinyl-intermediate, followed by Fe-catalyzed selective carbometalation to form a benzylic Grignard reagent.