1450627-48-1

Basic information

• Product Name: 6-amino-5-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-methoxyphenyl) methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
• Synonyms: 6-amino-5-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-methoxyphenyl) methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 1450627-48-1
• Molecular Weight: 435.436
• Mol File: 1450627-48-1.mol

Chemical Properties

• CAS DataBase Reference: 6-amino-5-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-methoxyphenyl) methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-5-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-methoxyphenyl) methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione(1450627-48-1)
• EPA Substance Registry System: 6-amino-5-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-methoxyphenyl) methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione(1450627-48-1)

Safety Data

• Hazardous Substances Data: 1450627-48-1(Hazardous Substances Data)

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 22105-09-5 4‐hydroxycoumarin 

Relevant articles and documents

One-pot three-component reaction for facile and efficient green synthesis of chromene pyrimidine-2,4-dione derivatives and evaluation of their anti-bacterial activity

Abstract: A facile and highly efficient one-pot three-component synthesis of chromene pyrimidine-2,4-dione derivatives from available substrates catalyzed by heteropoly acid (H3PW12O40) is described. In this protocol, the

Co3O4/NiO?GQD?SO3H nanocomposite as a superior catalyst for the synthesis of chromenpyrimidines

A three-component reaction involving aromatic aldehydes, 6-amino-1,3-dimethyluracil and 4-hydroxycoumarin was achieved in the presence of the Co3O4/NiO?GQD?SO3H nanocomposite as a highly effective heterogeneous catalyst to

l-Proline Derived Secondary Aminothiourea Organocatalyst for Synthesis of Coumarin Derived Trisubstituted Methanes: Rate Enhancement by Bifunctional Catalyst over Cooperative Catalysis

Abstract: Although l-proline derived aminothioureas are being used as catalyst in asymmetric synthesis, their applications in multicomponent reactions are not yet reported in the literature. We report herein a l-proline derived secondary aminothiourea as

An expedient synthesis of 6-amino-5-[(4-hydroxy-2-oxo-2H-chromen-3-yl)(aryl)methyl]-1,3-dimethyl-2,4,6(1H,3H)-pyrimidinedione derivatives using Fe3O4@TiO2 nanocomposite as an efficient, magnetically separable, and reusable

An efficient methodology dealing with the Fe3O4@TiO2 nanocomposite-catalyzed direct condensation reaction of 4-hydroxycoumarin, aromatic aldehydes, and 6-amino-1,3-dimethyluracil in aqueous media at room temperature is rep

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A one-pot, efficient synthesis of polyfunctionalized pyrido[2,3-d] pyrimidines and uncyclized adducts by aldehydes, 1,3-dicarbonyl compounds, and 6-aminouracils

A one-pot, efficient protocol for the synthesis of polyfunctionalized pyrido[2,3-d]pyrimidines and uncyclized adducts by 6-aminouracils in poly(ethylene glycol) 200/H2O or AcOH was described. An interesting family of pyrido[2,3-d]pyrimidines and uncyclized adducts bearing fused pharmacological active units are prepared. The reaction is free of toxic solvents and catalysts, has simple workup procedure, and has high atom economy, making it more environmentally friendly and suitable for large-scale operations.

Three-component green reaction of arylaldehydes, 6-Amino-1,3-dimethyluracil and active methylene compounds catalyzed by Zr(HSO4)4 Under solvent-free conditions

A convenient one-pot, three-component reaction of aromatic aldehydes, 6-amino-1,3-dimethyluracil and active methylene compounds in the presence of Zr(HSO4)4 as a heterogeneous catalyst, under solvent-free conditions brings a very sim