1450719-52-4Relevant academic research and scientific papers
Synthesis of 2-Alkylideneisochromans by Cyclocarbonylative Sonogashira Reactions
Aronica, Laura Antonella,Giannotti, Luca,Giuntini, Stefano,Caporusso, Anna Maria
, p. 6858 - 6862 (2014)
In this study we used a tandem carbonylative Sonogashira reaction/cyclisation process to construct alkylidene-functionalized isochromans in high yields with complete stereoselectivity (only Z isomers were formed). The reaction was performed in the absence
Gold-Catalyzed Ring Expansion of Enyne-Lactone: Generation and Transformation of 2-Oxoninonium
Luo, Kui,Cao, Tongxiang,Jiang, Huanfeng,Chen, Lianfen,Zhu, Shifa
supporting information, p. 5856 - 5859 (2017/11/10)
An efficient gold-catalyzed ring-expansion reaction of enyne-lactones to form 2-oxoninonium intermediates is reported. The 2-oxoninonium generated in this work could undergo further 6π electrocyclization and aromatization reaction to produce different aromatic compounds.
Palladium nanoparticles in glycerol: A versatile catalytic system for C-X bond formation and hydrogenation processes
Chahdoura, Faouzi,Pradel, Christian,Gomez, Montserrat
supporting information, p. 3648 - 3660 (2014/01/06)
Palladium nanoparticles stabilised by tris(3-sulfophenyl)phosphine trisodium salt in neat glycerol have been synthesised and fully characterised, starting from both Pd(II) and Pd(0) species. The versatility of this innovative catalytic colloidal solution has been proved by its efficient application in C-X bond formation processes (X=C, N, P, S) and C-C multiple bond hydrogenation reactions. The catalytic glycerol phase could be recycled more than ten times, preserving its activity and selectivity. The scope of each of these processes has demonstrated the power of the as-prepared catalyst, isolating the corresponding expected products in yields higher than 90%. The dual catalytic behaviour of this glycerol phase, associated to the metallic nanocatalysts used in wet medium (molecular- and surface-like behaviour), has allowed attractive applications in one-pot multi-step transformations catalysed by palladium, such as C-C coupling followed by hydrogenation, without isolation of intermediates using only one catalytic precursor. Copyright
Palladium-catalyzed alkyne insertion/reduction route to trisubstituted olefins
Fruchey, Erin R.,Monks, Brendan M.,Patterson, Andrea M.,Cook, Silas P.
supporting information, p. 4362 - 4365 (2013/09/24)
A new route to trisubstituted olefins through a palladium-catalyzed alkyne insertion/reduction reaction with unactivated alkyl iodides is reported. The reaction proceeds under mild conditions and tolerates a range of functional groups and substitution patterns. Preliminary mechanistic inquiry suggests that the transformation may proceed through a hybrid radical/organometallic pathway.
