145072-72-6

Basic information

• Product Name: o-chloro-p-nitrophenyl β-maltotetraoside
• CAS NO: 145072-72-6
• Molecular Weight: 822.125
• Mol File: 145072-72-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: o-chloro-p-nitrophenyl β-maltotetraoside(CAS DataBase Reference)
• NIST Chemistry Reference: o-chloro-p-nitrophenyl β-maltotetraoside(145072-72-6)
• EPA Substance Registry System: o-chloro-p-nitrophenyl β-maltotetraoside(145072-72-6)

Safety Data

• Hazardous Substances Data: 145072-72-6(Hazardous Substances Data)

Upstream product

• 127264-52-2 trideca-O-acetyl-α-maltotetraosyl bromide 
• 619-08-9 2-chloro-4-nitrophenol 
• 198561-63-6 2-chloro-4-nitrophenyl O-(α-D-glucopyranosyl)-(1->4)-tetrakis-[O-α-D-glucopyranosyl-(1->4)]-β-D-glucopyranoside 
• 90826-64-5 2-chloro-4-nitrophenyl β-maltoheptoside 
• 1263-76-9 maltotetraose 
• 120221-14-9 (2-chloro-4-nitrophenyl)-β-D-glucopyranoside 

Downstream Products

• 143206-27-3 2-chloro-4-nitrophenyl β-maltoside 
• 120221-14-9 (2-chloro-4-nitrophenyl)-β-D-glucopyranoside 
• 118291-90-0 (2R,3R,4S,5S,6R)-2-{(2R,3S,4R,5R,6R)-6-[(2R,3S,4R,5R,6S)-6-(2-Chloro-4-nitro-phenoxy)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy]-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy}-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 

Relevant articles and documents

Transglycosylation reaction of maltotriose-forming amylase from Streptomyces griseus

A maltotriose-forming amylase from Streptomyces griseus produced predominantly p-nitrophenyl α-maltotetraoside through a transglycosylation reaction from maltotetraose as a donor and p-nitrophenyl α-D-glucopyranoside as an acceptor in an organic co-solven

Chemoenzymatic preparation of 2-chloro-4-nitrophenyl β-maltooligosaccharide glycosides using glycogen phosphorylase b

In the present work, we aimed to develop a new chemoenzymatic procedure for the synthesis of β-maltooligosaccharide glycosides. The primer in the enzymatic reaction was 2-chloro-4-nitrophenyl β-maltoheptaoside (G7-CNP), which was synthesised from β-cyclodextrin (β-CD) using a very convenient chemical method [E. Farkas, L. Janossy, J. Harangi, L. Kandra, A. Liptak, Carbohydr. Res., 303 (1997) 407-415]. Shorter chain length CNP-maltooligosaccharides in the range of dp 3-6 were prepared using rabbit skeletal muscle glycogen phosphorylase b (EC 2.4.1.1). Detailed enzymological investigations revealed that the conversion of G7-CNP was highly dependent on the conditions of phosphorolysis. A 100% conversion of G7-CNP was achieved during 10 min in 1 M phosphate buffer (pH 6.8) at 30°C with the tetramer glycoside (77%) as the main product. Phosphorolysis at 10°C for 10 min resulted in 89% conversion and G4-, G5-, and G6-CNP oligomers were detected in the ratio of 29:26:34%, respectively. The reaction pattern was investigated using an HPLC system. The preparative scale isolation of G(3→6)-CNP glycosides was achieved by size-exclusion column chromatography (SEC) on Toyopearl HW-40 matrix. The productivity of the synthesis was improved by yields of up to 70-75%. Copyright (C) 1999 Elsevier Science Ltd.