145080-95-1 Usage
Uses
Used in Polymer Production:
(S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER is used as a monomer or a reactive intermediate for the production of polymers. Its isocyanate group facilitates the formation of polyurethanes and other polymeric materials, which are known for their durability and versatility in various applications.
Used in Adhesive and Coating Industries:
In the adhesive and coating industries, (S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER is used as a component in formulating strong and durable adhesives and coatings. Its reactive nature allows for the creation of robust bonds and protective layers on various surfaces.
Used in Pharmaceutical Manufacturing:
(S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER is utilized as an intermediate in the synthesis of pharmaceuticals. Its unique chemical structure contributes to the development of new drug molecules, potentially leading to advancements in medicinal chemistry.
Used in Agrochemical Development:
(S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER is also used in the agrochemical sector, where it serves as a building block for the synthesis of pesticides and other agrochemicals. Its reactivity and functional groups are harnessed to create effective and targeted products for agricultural use.
Used in Organic Chemistry Research:
Due to its distinctive structure and functional groups, (S)-(-)-2-ISOCYANATOGLUTARIC ACID DIETHYL ESTER holds potential for further research and development in organic chemistry. It can be explored for new reactions, mechanisms, and applications, contributing to the expansion of chemical knowledge and innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 145080-95-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,0,8 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145080-95:
(8*1)+(7*4)+(6*5)+(5*0)+(4*8)+(3*0)+(2*9)+(1*5)=121
121 % 10 = 1
So 145080-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO5/c1-3-15-9(13)6-5-8(11-7-12)10(14)16-4-2/h8H,3-6H2,1-2H3/t8-/m0/s1
145080-95-1Relevant academic research and scientific papers
Synthesis process of Raltitrexed key intermediate
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Paragraph 0047-0051, (2019/05/22)
The invention relates to the technical field of medicine preparation, in particular to a synthesis process of a Raltitrexed key intermediate. According to the synthesis process of the Raltitrexed keyintermediate, forming an active intermediate (isocyanate) through glutamate diethyl ester, the active intermediate and N-methyl-(2-thienyl) tert-butyl carbamate are directly reacted, and a target product N-[5-[N-(t-butyloxycarboryl)-N-methyl amino]-2-thenoyl]-L-glutamate diethyl ester is prepared by two steps. The synthesis process avoids difficulties of potential risks of part of racemization ofa chiral center caused by amidation reaction, low yield, complicated operation and purification and the like. The synthesis process of the Raltitrexed key intermediate is simple to operate, short in line, environmentally friendly and high in yield.
