1450824-22-2 Usage
Description
TD 139 is a compound that functions as a galactoside inhibitor of galectins, which are proteins involved in various cellular processes, including cell adhesion, cell growth, and cell death. It has been identified for its potential therapeutic applications, particularly in the treatment of pulmonary fibrosis.
Uses
Used in Pharmaceutical Industry:
TD 139 is used as a therapeutic agent for treating pulmonary fibrosis, a chronic and progressive lung disease characterized by the thickening and scarring of lung tissue. It specifically targets idiopathic pulmonary fibrosis in mammals, which is a form of the disease with no known cause.
The compound's ability to inhibit galectins makes it a promising candidate for the development of new treatments for pulmonary fibrosis, as these proteins have been implicated in the pathogenesis of the disease. By blocking the activity of galectins, TD 139 may help to reduce the inflammation and fibrosis associated with the condition, potentially improving the quality of life and life expectancy for patients suffering from pulmonary fibrosis.
Check Digit Verification of cas no
The CAS Registry Mumber 1450824-22-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,0,8,2 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1450824-22:
(9*1)+(8*4)+(7*5)+(6*0)+(5*8)+(4*2)+(3*4)+(2*2)+(1*2)=142
142 % 10 = 2
So 1450824-22-2 is a valid CAS Registry Number.
1450824-22-2Relevant articles and documents
LARGE SCALE PROCESS OF 3,3'-DIDEOXY-3,3'-BIS-[4-(3-FLUOROPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-1,1'-SULFANEDIYL-DI-BETA-D-GALACTOPYRANOSIDE
-
Page/Page column 34; 40-42; 44-46, (2021/01/23)
The present invention relates to a process for preparing a compound of formula (I), wherein said process is suitable for large scale synthesis.
SYNTHESIS OF 3-AZIDO-3-DEOXY-D-GALACTOPYRANOSE
-
Paragraph 0044-0046; 0053, (2020/12/30)
The present application provides a synthetic method for production of 3-azido-3-deoxy-D-galactopyranose. Also provided are methods of using the 3-azido-3-deoxy-D-galactopyranose in the manufacture of galactoside galectin antagonists, such as TD139 (GB0139), GB1107, GB2064, and GB1211.
GALACTOPYRANOSIDE DERIVATIVE
-
, (2019/01/06)
PROBLEM TO BE SOLVED: To provide galactopyranoside derivatives that can be used for the synthesis of various sugar derivatives. SOLUTION: The present invention provides a galactopyranoside derivative represented by formula (I) (R1's each represent -C (=O) R5, or are bound to each other to be a phenyl group-substituted methylene; R2 is hydroxylazide or the like; R3 is H, methyl, nitro or Cl; R4 is a phenylthio or bromo group). SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT
