145084-28-2 Usage
Uses
YM 022, is a potent, selective non-peptide antagonist of the gastrin/cholecystokinin (CCK)-B receptor. (Ki values are 68 pM and 63 nM at CCK2 and CCK1 receptors respectively).
Biological Activity
Extremely potent and highly selective non-peptide CCK 2 silent antagonist (K i values are 68 pM and 63 nM at CCK 2 and CCK 1 receptors respectively). Acts in vivo to potently inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation with a long duration of action.
Check Digit Verification of cas no
The CAS Registry Mumber 145084-28-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,0,8 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 145084-28:
(8*1)+(7*4)+(6*5)+(5*0)+(4*8)+(3*4)+(2*2)+(1*8)=122
122 % 10 = 2
So 145084-28-2 is a valid CAS Registry Number.
145084-28-2Relevant articles and documents
Benzodiazepine aryl urea derivatives
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, (2008/06/13)
This invention relates to novel benzodiazepine derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof, STR1 (wherein R 1 is an aryl group, or an aromatic heterocyclic radical of 5-membered monocyclic, 6-m