1450903-80-6

Basic information

• Product Name: (2R,3R)-bis(2-iodo-3-nitrophenoxyl)butane
• CAS NO: 1450903-80-6
• Molecular Weight: 584.106
• Mol File: 1450903-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-bis(2-iodo-3-nitrophenoxyl)butane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-bis(2-iodo-3-nitrophenoxyl)butane(1450903-80-6)
• EPA Substance Registry System: (2R,3R)-bis(2-iodo-3-nitrophenoxyl)butane(1450903-80-6)

Safety Data

• Hazardous Substances Data: 1450903-80-6(Hazardous Substances Data)

Upstream product

• 197243-48-4 2-iodo-3-nitrophenol 
• 74839-83-1 (2S,3S)-bis(4-methylbenzenesulfonyl)butane 

Relevant articles and documents

Enantiomeric recognition of amino acid salts by macrocyclic crown ethers derived from enantiomerically pure 1,8,9,16-tetrahydroxytetraphenylenes

Asymmetric synthesis of (R,R)- and (S,S)-1,8,9,16- tetrahydroxytetraphenylenes was achieved from starting material (2R,3R)-butane-2,3-diol and (2S,3S)-butane-2,3-diol respectively by utilizing a center-to-axis strategy. A series of crown ether compounds 20, 24, and 25 and their corresponding enantiomers derived from chiral tetrahydroxytetraphenylene were synthesized in enantiomerically pure forms. Enantiomeric recognition properties of these hosts toward l- and d-amino acid methyl ester hydrochloride were studied by the UV spectroscopy titration. The tetramer hosts (S,S,S,S,S,S,S,S)-20 and (R,R,R,R,R,R,R,R)-20 exhibited the best enantioselectivities toward l- and d-alanine methyl ester hydrochloride salt with KL/KD = 4.1 and KD/KL = 3.9, respectively. The new chiral macrocyclic hosts would further enrich the host-guest chemistry.