1451010-35-7

Basic information

• Product Name: (4-(4-(1-(2-chloro-2-(4-chlorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)phenyl)methanamine
• Synonyms: (4-(4-(1-(2-chloro-2-(4-chlorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)phenyl)methanamine
• CAS NO: 1451010-35-7
• Molecular Weight: 482.415
• Mol File: 1451010-35-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-(4-(1-(2-chloro-2-(4-chlorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)phenyl)methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(4-(1-(2-chloro-2-(4-chlorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)phenyl)methanamine(1451010-35-7)
• EPA Substance Registry System: (4-(4-(1-(2-chloro-2-(4-chlorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)phenyl)methanamine(1451010-35-7)

Safety Data

• Hazardous Substances Data: 1451010-35-7(Hazardous Substances Data)

Upstream product

• 1451010-33-5 2-(4-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(4-chlorophenyl)ethanol 
• 1451010-30-2 2-(4-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(4-chlorophenyl)ethanone 
• 109-01-3 1-methyl-piperazine 
• 623-00-7 4-bromobenzenecarbonitrile 
• 34334-28-6 4-(4-methylpiperazin-1-yl)benzonitrile 
• 216144-45-5 (4-(4-methylpiperazin-1-yl)phenyl)methanamine 
• 1013930-74-9 4-chloro-1-[2-chloro-2-(4-chlorophenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines

A versatile approach for the synthesis of 1,4-disubstituted pyrazolo[3,4-d]pyrimidines has been developed. Starting from commercially available allopurinol, TBAF mediated N1-functionalization and subsequent C4 nucleophilic substitution, under microwave assisted- or standard heating conditions, granted access to highly functionalized pyrazolo[3,4-d]pyrimidines of potential biological interest.