145104-77-4

Upstream product

• 145104-70-7 (1R,5R)-3,3-dibromo-6,6-dimethylbicyclo<3.1.1>-heptan-2-one 
• 38651-65-9 (1R,5S)-(+)-nopinone 
• 58738-65-1 1,3-dimethoxy-5-[5'-(2H₃)-pentyl]benzene 
• 145104-71-8 (1R,5R)-3-bromo-6,6-dimethylbicyclo<3.1.1>-hept-3-en-2-one 

Downstream Products

• 145104-80-9 3-<2,6-dimethoxy-4-(5'-((2)H3)pentyl)phenyl>-4-isopropenyl-1-(((trifluoromethyl)sulfonyl)oxy)cyclohex-1-ene 
• 145104-79-6 2-bromo-3-<(2,6-dimethoxy-4-(5'-(2)H3)pentyl)phenyl>-4-isopropenyl-cyclohexan-1-one 
• 145104-78-5 2-bromo-3-<(2,6-dimethoxy-4-(5'-(2)H3)pentyl)phenyl>-4-isopropenyl-cyclohexan-1-ethylene ketal 

Relevant academic research and scientific papers

Synthesis of 5'-((2)H3)-(-)-11-Nor-9-carboxy-Δ9-Tetrahydrocannabinol Methyl Ester Methyl Ether

A synthesis of 5'-((2)H3)-(-)-11-nor-carboxy-δ9-tetrahydrocannabinol methyl ester methyl ether (4) has been accomplished from α-bromoenone 10.The key steps are the stereocontrolled cyclobutane ring opening of the cuprate adduct 18 and the cyclization of the cyclohexenyl triflate 21 with excess iodotrimethylsilane to produce Δ9-cylohexenyl triflate 22.An efficient, stereospecific synthesis of optically active (-)-11-nor-9-keto-hexahydrocannabinol (8) has also been accomplished.