58738-65-1

Upstream product

• 41251-37-0 methyl-d3-magnesium iodide 
• 111540-03-5 4-(3,5-dimethoxyphenyl)-1-bromobutane 
• 58545-58-7 (2E,4E)-5-(3,5-Dimethoxy-phenyl)-penta-2,4-dienoic acid methyl ester 
• 111540-02-4 1-(but-3-en-1-yl)-3,5-dimethoxybenzene 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 107153-18-4 4-(3,5-dimethoxyphenyl)-1-butanol 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 504396-89-8 1,3-dimethoxy-5-[3'-hydroxy-5'-(2H₃)-pentyl]benzene 
• 125187-47-5 3-(3,5-dimethoxyphenyl)-1-propanal 
• 504396-91-2 1,3-dimethoxy-5-[3'-(methanesulfonyloxy)-5'-(2H₃)-pentyl]benzene 
• 145104-80-9 3-<2,6-dimethoxy-4-(5'-((2)H3)pentyl)phenyl>-4-isopropenyl-1-(((trifluoromethyl)sulfonyl)oxy)cyclohex-1-ene 
• 891-66-7 5-(3,5-Dimethoxy-phenyl)-valeriansaeuremethylester 
• 58545-59-8 C₁₃H₁₈⁽²⁾H₂O₃ 

Downstream Products

• 145104-77-4 3-bromo-4-<(2,6-dimethoxy-4-(5'-(2)H3)pentyl)phenyl>-6,6-dimethylbicyclo<3.1.1>-hept-2-one 
• 58545-61-2 1,3-dihydroxy-5-[5'-(2H₃)-pentyl]benzene 
• 145104-80-9 3-<2,6-dimethoxy-4-(5'-((2)H3)pentyl)phenyl>-4-isopropenyl-1-(((trifluoromethyl)sulfonyl)oxy)cyclohex-1-ene 
• 145104-78-5 2-bromo-3-<(2,6-dimethoxy-4-(5'-(2)H3)pentyl)phenyl>-4-isopropenyl-cyclohexan-1-ethylene ketal 
• 145104-79-6 2-bromo-3-<(2,6-dimethoxy-4-(5'-(2)H3)pentyl)phenyl>-4-isopropenyl-cyclohexan-1-one 

Relevant academic research and scientific papers

Synthesis of side chain specifically deuterated (-)-Δ9-tetrahydrocannabinols

(-)-Δ9-Tetrahydrocannabinols specifically deuterated at the n-pentyl side chain were prepared using the corresponding resorcinols as key intermediates. To obtain the deuterated resorcinols we developed conditions under which no deuterium scramb

Synthesis of 5'-((2)H3)-(-)-11-Nor-9-carboxy-Δ9-Tetrahydrocannabinol Methyl Ester Methyl Ether

A synthesis of 5'-((2)H3)-(-)-11-nor-carboxy-δ9-tetrahydrocannabinol methyl ester methyl ether (4) has been accomplished from α-bromoenone 10.The key steps are the stereocontrolled cyclobutane ring opening of the cuprate adduct 18 and the cyclization of the cyclohexenyl triflate 21 with excess iodotrimethylsilane to produce Δ9-cylohexenyl triflate 22.An efficient, stereospecific synthesis of optically active (-)-11-nor-9-keto-hexahydrocannabinol (8) has also been accomplished.

A simple and efficient synthesis of 5'-(2H3)olivetol

The title compound 1 was prepared in 13percent overall yield starting from the commercially available and inexpensive 3,5-dimethoxybenzoic acid (4).The n-pentyl side chain was elaborated from cross-coupling reactions between halides.