145104-99-0 Usage
Uses
Used in Pharmaceutical Synthesis:
Pyrrolidine, 3-(3-nitrophenyl)-1-(phenylmethyl)is utilized as a key intermediate in the production of various pharmaceuticals, specifically for the development of analgesics and antiviral drugs. Its unique structure allows it to contribute to the medicinal properties of these drugs, enhancing their efficacy and therapeutic potential.
Used in Organic Chemistry Research:
Pyrrolidine, 3-(3-nitrophenyl)-1-(phenylmethyl)serves as a valuable building block in organic chemistry, facilitating the synthesis of novel compounds and contributing to the advancement of chemical research. Its versatility in reactions makes it a promising candidate for the development of new chemical entities with potential applications across various fields.
Used in Drug Development:
Pyrrolidine, 3-(3-nitrophenyl)-1-(phenylmethyl)has been the focus of research for its potential therapeutic applications. Its role in the development of new drugs is significant, as it may lead to the discovery of innovative treatments for a range of conditions, further expanding the horizons of medical science.
Check Digit Verification of cas no
The CAS Registry Mumber 145104-99-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,0 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 145104-99:
(8*1)+(7*4)+(6*5)+(5*1)+(4*0)+(3*4)+(2*9)+(1*9)=110
110 % 10 = 0
So 145104-99-0 is a valid CAS Registry Number.
145104-99-0Relevant academic research and scientific papers
Tetrahydropyrrole compound, preparation method, pharmaceutical composition and application thereof
-
Paragraph 0408; 0414-0417, (2019/07/16)
The invention discloses a tetrahydropyrrole compound and a preparation method, a pharmaceutical composition and application thereof. The tetrahydropyrrole compound of the invention is as shown in thegeneral formula (I). The tetrahydropyrrole compound of the invention has an excellent inhibitory effect on the positive symptom of schizophrenia, and has equivalent or stronger efficacy in comparisonwith the positive medicine olanzapine. In addition, the compound of the invention has a dual inhibitory effect on a D2 receptor and a DAT receptor, can effectively treat schizophrenia and improve negative symptoms and cognitive functions, and helps reduce side-effect of centrum and secretion of lactogen.
3-Arylpyrrolidines via azomethine ylide 1,3-dipolar cycloaddition to styrenes
Laborde, Edgardo
, p. 6607 - 6610 (2007/10/02)
Monosubstituted olefins conjugated to an aromatic or heteroaromatic ring undergo 1,3-dipolar cycloaddition with the azomethie ylide derived from N-benzyl-N-(methoxymethyl)trimethylsilylamine to give 3-aryl- and 3-hetero-arylpyrrolidines in good to excellent yield.
