1451049-49-2Relevant academic research and scientific papers
LPA RECEPTOR ANTAGONISTS AND USES THEREOF
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, (2021/12/31)
The present disclosure relates generally to compounds that bind to Lysophosphatidic Acid Receptor 1 (LPAR1) and act as antagonists of LPAR1. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of LPAR1, including fibrosis and liver diseases such as non-alcoholic steatohepatitis (NASH), interstitial lung disease (ILD), or chronic kidney disease (CKD).
Synthesis of mono-fluorinated functionalized cyclopropanes and aziridines using the α-fluorovinyl diphenyl sulfonium salt
Hirotaki, Kensuke,Takehiro, Yui,Kamaishi, Ryo,Yamada, Yasunori,Hanamoto, Takeshi
, p. 7965 - 7967 (2013/09/02)
The α-fluorovinyl diphenyl sulfonium salt 1 is attractive due to its high potential for the synthesis of mono-fluorinated cyclopropanes and aziridines as useful three-membered rings. The synthetically useful salt 1 is readily prepared from α-fluorovinyl p
