1451053-27-2Relevant academic research and scientific papers
Pd(ii)-SDP-catalyzed enantioselective 5-exo-dig cyclization of γ-alkynoic acids: Application to the synthesis of functionalized dihydofuran-2(3H)-ones containing a chiral quaternary carbon center
Sridharan, Vellaisamy,Fan, Lulu,Takizawa, Shinobu,Suzuki, Takeyuki,Sasai, Hiroaki
, p. 5936 - 5943 (2013/09/12)
The Pd(ii)-SDP-catalyzed first enantioselective intramolecular cyclization of α,α-disubstituted γ-alkynoic acids is described. This 5-exo-dig cyclization afforded dihydrofuran-2(3H)-ones bearing a chiral quaternary carbon center in excellent yields with e
