1451073-75-8Relevant academic research and scientific papers
Stereospecific syntheses of enaminonitriles and β-Enaminoesters via Domino Ring-Opening Cyclization (DROC) of Activated Cyclopropanes with Pronucleophilic Malononitriles
Saha, Amrita,Bhattacharyya, Aditya,Talukdar, Ranadeep,Ghorai, Manas K.
, p. 2131 - 2144 (2018/02/23)
Two novel synthetic protocols for the syntheses of highly functionalized five-membered carbocyclic enaminonitriles and β-enaminoesters have been developed via domino ring-opening cyclization (DROC) and DROC/decarboxylative tautomerization of activated cyc
An efficient synthetic route to carbocyclic enaminonitriles via Lewis acid catalysed domino-ring-opening-cyclisation (DROC) of donor-acceptor cyclopropanes with malononitrile
Ghorai, Manas K.,Talukdar, Ranadeep,Tiwari, Deo Prakash
supporting information, p. 8205 - 8207 (2013/09/12)
A highly efficient strategy for the synthesis of functionalised carbocyclic enaminonitriles in excellent yields has been described. The reaction utilises Yb(OTf)3 catalysed C-C bond cleavage and two simultaneous C-C bond formations of donor-acceptor (DA)-cyclopropanes with malononitrile anions in a domino fashion.
