1451091-06-7Relevant academic research and scientific papers
Nickel(II)-Catalyzed Asymmetric Michael Addition of Oxindoles with Modified N,N,O-Tridentate Chiral Phenanthroline Ligands
Naganawa, Yuki,Abe, Hiroki,Nishiyama, Hisao
supporting information, p. 1973 - 1978 (2016/08/09)
Nickel(II)-catalyzed enantioselective Michael addition of N-Boc-oxindole derivatives with methyl vinyl ketone was demonstrated to give the corresponding adducts having chiral all-carbon quaternary centers with up to 87% ee in the presence of axially chira
Chiral phosphine catalyzed asymmetric michael addition of oxindoles
Zhong, Fangrui,Dou, Xiaowei,Han, Xiaoyu,Yao, Weijun,Zhu, Qiang,Meng, Yuezhong,Lu, Yixin
supporting information, p. 943 - 947 (2013/02/23)
Bifunctional phosphines derived from amino acids mediate the asymmetric Michael addition of 3-substituted oxindoles to activated alkenes (see scheme). Biologically relevant chiral 3,3-disubstituted oxindoles were thus prepared in high yields and with exce
