145121-60-4Relevant academic research and scientific papers
Stereocontrolled synthesis of spirosuccinimide derivative of (+)-hydantocidin
Sano, Hiromi,Mio, Shigeru,Tsukaguchi, Naoto,Sugai, Soji
, p. 1387 - 1394 (1995)
Synthesis of the spirosuccinimide derivative of (+)-hydantocidin 2 is reported. The key step is a SnCl4-promoted C-glycosidation of the protected D-psicose 3 with allyltrimethylsilane in dichloromethane, which proceeded in good yield and high selectivity; however, C-glycosidation of 3 in acetonitrile afforded the spirooxazoline 6. Synthesis of 2 was achieved in 13% overall yield from 3.
