145124-62-5

Upstream product

• 134001-66-4 (S)-N-(1-methylethyl)-3-hydroxybutyramide 
• 1499-19-0 benzylphosphonic dichloride 
• 145124-75-0 (S)-N-(1-methylethyl)-4-amino-2-butanol 

Downstream Products

• 172878-09-0 (S)-(2l,6l,1'u)-2-(1',2'-diphenylethyl)-3-(1-methylethyl)-6-methyl-1,3,2-oxazaphosphorinane 2-sulfide 
• 172878-13-6 (S)-(2l,6l,1'u)-6-methyl-3-(1-methylethyl)-2-(1'-phenylethyl)-1,3,2-oxazaphosphorinane 2-sulfide 
• 184535-63-5 (R)-(1-phenylethyl)phosphonic acid 
• 156406-83-6 (S)-(2u,6l,1'u)-3-(1-methylethyl)-2-(1'-phenylethyl)-6-methyl-1,3,2-oxazaphosphorinane 2-oxide 
• 172878-06-7 (S)-(2l,6l)-6-methyl-3-(1-methylethyl)-2-(phenylmethyl)-1,3,2-oxazaphosphorinane 2-sulfide 
• 156406-87-0 (S)-(2u,6l,1'u)-2-(1',2'-diphenylethyl)-3-(1-methylethyl)-6-methyl-1,3,2-oxazaphosphorinane 2-oxide 

Relevant academic research and scientific papers

Alkylations of chiral, phosphoryl- and thiophosphoryl-stabilized carbanions

A general method for the preparation of enantiomerically enriched phosphonic acids and phosphonates with three different α-substitution patterns (aryl, alkyl, and alkoxy) has been developed. Anions derived from enantiomerically enriched thiophosphonamidat

Alkylation of Chiral, Phosphorus-Stabilized Carbanions: Substituent Effects on the Alkylation Selectivity

The alkylation of a series of enantiomerically pure cis and trans 3-substituted 2-benzyl-6-methyl-1,3,2-oxazaphosphorinane 2-oxides was found to be sensitive to the bulk of the N-substituents.