1451372-05-6

Basic information

• Product Name: methyl 2-fluoro-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoate
• Synonyms: methyl 2-fluoro-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoate
• CAS NO: 1451372-05-6
• Molecular Weight: 469.556
• Mol File: 1451372-05-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-fluoro-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-fluoro-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoate(1451372-05-6)
• EPA Substance Registry System: methyl 2-fluoro-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoate(1451372-05-6)

Safety Data

• Hazardous Substances Data: 1451372-05-6(Hazardous Substances Data)

Upstream product

• 83780-47-6 (-)-(R)-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 
• 4940-39-0 acide chromone carboxylique-2 
• 51939-71-0 chroman-2-carboxylic acid 
• 1451373-96-8 (2R)-2-(((tert-butoxycarbonyl)((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)-2H-chromen-4-yl trifluoromethanesulfonate 
• 1451373-95-7 tert-butyl ((R)-1-(naphthalen-1-yl)ethyl)(((R)-4-oxochroman-2-yl)methyl)carbamate 
• 1451373-94-6 tert-butyl ((R)-chroman-2-ylmethyl)((R)-1-(naphthalen-1-yl)ethyl)carbamate 
• 1451373-93-5 (R)-N-((R)-chroman-2-ylmethyl)-1-(naphthalen-1-yl)ethanamine 
• 227466-91-3 (R)-chroman-2-carboxylic acid chloride 
• 1451373-92-4 (R)-N-((R)-1-(naphthalen-1-yl)ethyl)chroman-2-carboxamide 
• 1451374-16-5 methyl 5-((2R)-2-(((tert-butoxycarbonyl)((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)-2H-chromen-4-yl)-2-fluorobenzoate 

Relevant articles and documents

SUBSTITUTED CHROMAN COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS

The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.