1451376-08-1Relevant academic research and scientific papers
Asymmetric α-arylation of amino acid derivatives by clayden rearrangement of ester enolates via memory of chirality
Tomohara, Keisuke,Yoshimura, Tomoyuki,Hyakutake, Ryuichi,Yang, Pan,Kawabata, Takeo
, p. 13294 - 13297 (2013/09/24)
A method for asymmetric α-arylation of amino acid derivatives has been developed. The arylation was performed by Clayden rearrangement of ester enolates via memory of chirality to give hydantoins with an aryl-substituted tetrasubstituted carbon with up to 99% ee.
