1451391-20-0 Usage
General Description
2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a chemical compound with the molecular formula C15H17BF3N. It is a fluoroaniline derivative, commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,3,4-Trifluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is often employed as a reagent in organic chemistry, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Its unique structure, with a dioxaborolane moiety, makes it a valuable building block in the synthesis of complex molecules for various applications in the field of medicinal chemistry and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1451391-20-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,1,3,9 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1451391-20:
(9*1)+(8*4)+(7*5)+(6*1)+(5*3)+(4*9)+(3*1)+(2*2)+(1*0)=140
140 % 10 = 0
So 1451391-20-0 is a valid CAS Registry Number.
1451391-20-0Relevant articles and documents
Synthesis and biological evaluation of A-ring biaryl-carbamate analogues of rhazinilam
Baudoin, Olivier,Claveau, Fabien,Thoret, Sylviane,Herrbach, Audrey,Guenard, Daniel,Gueritte, Francoise
, p. 3395 - 3400 (2007/10/03)
An improvement of the synthesis of biphenyl-carbamate 2a, the most active analogue of rhazinilam 1 so far, was performed using the Pd-catalyzed borylation/Suzuki coupling (BSC) method developed in our laboratories. The preparation of A-ring analogues of 2a bearing electron-withdrawing or donating groups is reported according to this new synthetic scheme. The antitubulin properties as well as the cytotoxicity of these compounds toward human cancer cell lines were evaluated in comparison with rhazinilam and 2a.
