122375-82-0

Basic information

• Product Name: 2-BROMO-4,5,6-TRIFLUOROANILINE
• Synonyms: 2-BROMO-4,5,6-TRIFLUOROANILINE;2-BROMO-4,5,6-TRIFLUOROANLINE;6-BROMO-2,3,4-TRIFLUOROANILINE;6-Bromo-2,3,4-trifluoroaniline 98%;6-Bromo-2,3,4-trifluoroaniline98%;2-BroMo-4,5,6-trifluoroaniline
• CAS NO: 122375-82-0
• Molecular Formula: C6H3BrF3N
• Molecular Weight: 225.99
• Product Categories: Miscellaneous;Fluorine series
• Mol File: 122375-82-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 58-60 °C(lit.)
• Boiling Point: 213.545 °C at 760 mmHg
• Flash Point: 82.949 °C
• Appearance: /
• Density: 1.875 g/cm⁴⁸
• Vapor Pressure: 0.619mmHg at 25°C
• Refractive Index: 1.508
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-BROMO-4,5,6-TRIFLUOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4,5,6-TRIFLUOROANILINE(122375-82-0)
• EPA Substance Registry System: 2-BROMO-4,5,6-TRIFLUOROANILINE(122375-82-0)

Safety Data

• Hazard Codes: Xn,Xi,T
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 122375-82-0(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline

InChI:InChI=1/C6HBrClF3/c7-2-1-3(9)5(10)6(11)4(2)8/h1H

Upstream product

• 393-79-3 1,3-dichloro-2-fluoro-4-nitrobenzene 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 20098-48-0 3,4,5-trichloronitrobenzen 
• 3107-19-5 3,5-dichloro-4-fluoro-nitrobenzene 
• 2729-34-2 3,5-dichloro-4-fluorophenylamine 
• 2268-05-5 1,3-dichloro-2-fluorobenzene 
• 3862-73-5 2,3,4-trifluoroaniline 

Downstream Products

• 138526-69-9 3,4,5-trifluoro-1-bromobenzene 

Relevant articles and documents

Green synthesis method of 3,4,5-trifluorobromobenzene

The invention discloses a green synthesis method of 3,4,5-trifluorobromobenzene. The green synthesis method comprises the following steps: adding 2,3,4-trifluoroaniline and water into a reactor, adding hydrobromic acid and hydrogen peroxide, and carrying out a hybrid reaction to obtain 2,3,4-trifluoro-6-bromoaniline after the reaction is ended; slowly adding a sulfuric acid solution of nitroso sulfuric acid into the prepared 2,3,4-trifluoro-6-bromoaniline, and carrying out a diazotization reaction to obtain a diazonium salt solution; and adding sodium hypophosphite and porous material-loaded copper oxide into the prepared diazonium salt solution as catalysts, conducting reacting, and sequentially carrying out distillation, alkali washing, water washing and reduced-pressure rectification on reaction liquid after the reaction is finished so as to obtain a target product. According to the method, nitrososulfuric acid replaces sodium nitrite to serve as a diazotization reagent, so no high-salt wastewater is discharged, production cost is reduced, and the method is more environmentally friendly; and hydrobromic acid serves as a bromine source, and hydrogen peroxide is added, so the utilization rate of bromine atoms is high, the adding amount of hydrobromic acid is reduced, and the amount of three wastes generated in implementation of the method is remarkably reduced.