1451423-04-3

Basic information

• Product Name: C₂₁H₂₃N₃O₃S
• CAS NO: 1451423-04-3
• Molecular Weight: 397.498
• Mol File: 1451423-04-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₃N₃O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₃N₃O₃S(1451423-04-3)
• EPA Substance Registry System: C₂₁H₂₃N₃O₃S(1451423-04-3)

Safety Data

• Hazardous Substances Data: 1451423-04-3(Hazardous Substances Data)

Upstream product

• 13220-41-2 6-methoxy-3-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 5234-30-0 glycozoline 

Relevant articles and documents

A tandem reduction-oxidation protocol for the conversion of 1-keto-1,2,3,4-tetrahydrocarbazoles to carbazoles via tosylhydrazones through microwave assistance: Efficient synthesis of glycozoline, clausenalene, glycozolicine, and deoxycarbazomycin B and the total synthesis of murrayafoline A

A novel and efficient methodology for the synthesis of carbazoles from 1-keto-1,2,3,4-tetrahydrocarbazoles via the corresponding tosylsulfonhydrazones by a one-pot tandem reduction-oxidation protocol using a combination of NaBH4 and Pd-C on MgSO4·7H2O, a solid support, under microwave is developed. The reaction is successfully extended toward the synthesis of several naturally occurring carbazole alkaloids, namely 3-methylcarbazole, glycozoline, clausenalene, glycozolicine, murrayafoline A, and deoxycarbazomycin B, a carbazole derivative that is known to have a promising antimicrobial activity.