145157-87-5

Basic information

• Product Name: 4-AMINO-4'-TERT BUTYL DIPHENYL ETHER
• Synonyms: 4-[4-(TERT-BUTYL)PHENOXY]ANILINE;4-AMINO-4'-TERT BUTYL DIPHENYL ETHER;4-(4-butylphenoxy)Benzenamine
• CAS NO: 145157-87-5
• Molecular Formula: C₁₆H₁₉NO
• Molecular Weight: 241.32816
• Mol File: 145157-87-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-AMINO-4'-TERT BUTYL DIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-4'-TERT BUTYL DIPHENYL ETHER(145157-87-5)
• EPA Substance Registry System: 4-AMINO-4'-TERT BUTYL DIPHENYL ETHER(145157-87-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 145157-87-5(Hazardous Substances Data)

Usage

General Description

4-Amino-4'-tert butyl diphenyl ether is a chemical compound with the molecular formula C16H19NO. It is an ether with a phenyl ring and an amino group attached to it. 4-AMINO-4'-TERT BUTYL DIPHENYL ETHER is commonly used as a stabilizer in the manufacturing of polymers and plastics. It is also employed in the synthesis of pharmaceuticals and agrochemicals. Additionally, it can act as an antioxidant and ultraviolet absorber in various industrial applications. However, it is important to handle this compound with care as it can be harmful if ingested or inhaled and may cause skin and eye irritation upon contact.

Upstream product

• 1638-22-8 4-n-butylphenol 
• 2106-50-5 2-chloro-4-fluoro-1-nitrobenzene 
• 50829-60-2 C₁₆H₁₇NO₃ 

Downstream Products

• 1244974-91-1 C₄₅H₃₅F₆N₃O₈ 

Relevant articles and documents

Synthesis of N-Substituted Iminosugar Derivatives and Evaluation of Their Immunosuppressive Activities

It is important to find more effective and safer immunosuppressants, because clinically used immunosuppressive agents have significant side effects. A series of N-substituted iminosugar derivatives were designed and synthesized, and their immunosuppressive effects were evaluated by the CCK-8 assay. The results revealed that iminosugars 10 e and 10 i, that is, (3R,4S)-1-(4-heptyloxylphenylethyl)pyrrolidine-3,4-diol and (3R,4S)-1-[2-(2-chloro-4-(p-tolylthio)-phenyl-1-yl)ethyl]pyrrolidine-3,4-diol, respectively, exhibited the strongest inhibitory effects on mouse splenocyte proliferation (IC50=2.16 and 2.48 μm, respectively), whereas the iminosugars containing an amide group near the hydrophilic head (compounds 10 j–n) exhibited no inhibitory effects. Further studies revealed that the inhibitory effects on splenocyte proliferation may have come from the suppression of both IFN-γ and IL-4 cytokines. Our results suggest that synthetic iminosugars, especially compounds 10 e and 10 i, hold potential as immunosuppressive agents.