145162-48-7

Upstream product

• 81945-73-5 1H-pyrazol-1-ol 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 145162-51-2 1-(p-methoxyphenyl)methyl-pyrazole 

Downstream Products

• 384339-36-0 3-(2-nitrophenyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-34-8 3-(4-nitrophenyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-33-7 3-(4-methoxyphenyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-35-9 3-(4-methylphenyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-37-1 3-(2-fluorophenyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-38-2 3-(2-pyridyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 384339-39-3 3-(2-thienyl)-2-(4-methoxybenzyl)pyrazole-1-oxide 
• 438193-76-1 2-(4-methoxy)-5-(4-methoxyphenyl)-3-(4-methylphenyl)-4-(4-nitrophenyl)pyrazole-1-oxide 
• 438193-74-9 4-(4-fluorophenyl)-2-(4-methoxybenzyl)-5-(4-methoxyphenyl)-3-(4-methylphenyl)pyrazole-1-oxide 
• 438193-72-7 4-bromo-2-(4-methoxybenzyl)-5-(4-methoxyphenyl)-3-(4-methylphenyl)pyrazole-1-oxide 
• 438193-70-5 3,4-dibromo-2-(4-methoxybenzyl)-5-(4-methoxyphenyl)pyrazole-1-oxide 
• 1027039-30-0 4-bromo-2-(4-methoxy-benzyl)-1-oxy-5-trimethylsilanyl-2H-pyrazole-3-carbaldehyde 
• 499109-50-1 2-(4-methoxybenzyl)pyrazolo[3,4-c]quinoline 1-oxide 

Relevant academic research and scientific papers

Synthesis of 2-Alkylpyrazole-1-oxides: A Facile Access to 1-Alkyl-5-halopyrazoles

Selective N-alkylation of 1-hydroxypyrazole 1 into the corresponding 2-alkyl-pyrazole-1-oxides 2a-f has been achieved by treatment with alkyl bromides in the absence of base. Subsequent deoxygenation/halogenation into 1-alkyl-5-halopyrazoles 3a-d and 4a-d using phosphorus oxyhalides is described.

2-Substituted Pyrazole 1-Oxides. Preparation and Reaction with Electrophilic Reagents

1-Substituted pyrazoles have been oxidized by peracids to 2-substituted pyrazole 1-oxides.This leads to a change in reactivity towards electrophilic attack. 2-Benzylpyrazole 1-oxide is brominated, chlorinated, and nitrated selectively at C-3.The 3-halo-su