145162-51-2

Basic information

• Product Name: CHEMPACIFIC 41266
• Synonyms: CHEMPACIFIC 41266;1-(4-METHOXY-BENZYL)-1H-PYRAZOLE;4-METHOXYBENZYL-PYRAZOLE;1-(4-METHOXYBENZYL)PYRAZOLE
• CAS NO: 145162-51-2
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.22578
• Mol File: 145162-51-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CHEMPACIFIC 41266(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMPACIFIC 41266(145162-51-2)
• EPA Substance Registry System: CHEMPACIFIC 41266(145162-51-2)

Safety Data

• Hazardous Substances Data: 145162-51-2(Hazardous Substances Data)

Upstream product

• 288-13-1 NH-pyrazole 
• 824-94-2 p-methoxybenzyl chloride 
• 288-32-4 1H-imidazole 
• 623-12-1 4-chloromethoxybenzene 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 104-01-8 4-Methoxyphenylacetic acid 
• 64841-16-3 3-{N'-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-hydrazino}-propionitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 140-69-2 4-methoxybenzylhydrazine 

Downstream Products

• 861161-12-8 2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butan-1-ol 
• 861161-22-0 1-(1-(4-methoxybenzyl)-1H-pyrazol-5-yl)ethan-1-ol 
• 861161-38-8 1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butan-1-ol 
• 861161-30-0 1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]-2-methylpropan-1-ol 
• 1446114-13-1 ethyl 1-(4-methoxybenzyl)-6-(phenylamino)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate 
• 1426934-84-0 C₂₁H₁₇N₃O₃ 
• 1426934-85-1 C₂₀H₁₅N₃O₃ 
• 1426934-82-8 C₂₁H₁₈N₄O₃ 
• 1174876-30-2 ethyl 1-(4-methoxybenzyl)-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate 
• 1426934-81-7 ethyl 1-(4-methoxybenzyl)-6-(trifluoromethylsulfonyloxy)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate 
• 1426934-83-9 ethyl 1-(4-methoxybenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate 
• 1030615-71-4 (1-(4-methoxybenzyl)-1H-pyrazol-5-yl)(o-tolyl)methanone 
• 153687-35-5 1-(4-methoxybenzyl)-1H-pyrazole-4-carbaldehyde 
• 162468-77-1 1-(4-methoxybenzyl)pyrazole-5-carboxaldehyde 

Relevant articles and documents

Boron carbonitride photocatalysts for direct decarboxylation: The construction of C(sp3)-N or C(sp3)-C(sp2) bonds with visible light

A metal-free protocol is established for the decarboxylative N-H or C(sp2)-H functionalization of acidsviametal-free boron carbon nitride (BCN) photocatalysis, delivering the desired products under ambient conditions. This methodology is applicable to the late-stage modification of pharmaceutical molecules and gram-scale experiments as well as in the recovery and reuse of the photocatalysts without the loss of reactivity. The developed photochemical reaction system fulfills the requirements of green and sustainable chemistry.

Suzuki-miyaura cross-coupling of potassium trifluoro(N -methylheteroaryl) borates with aryl and heteroaryl halides

The synthesis of potassium trifluoro(N-methylheteroaryl)borates and their use in cross-coupling reactions with various aryl and heteroaryl halides to construct N-methyl heteroaryl-substituted aromatic and heteroaromatic compounds are reported.

Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide γ-secretase inhibitors

γ-Secretase inhibitors have been shown to reduce the production of β-amyloid, a component of the plaques that are found in brains of patients with Alzheimer's disease. A novel series of heterocyclic sulfonamide γ-secretase inhibitors that reduce β-amyloid levels in cells is reported. Several examples of compounds within this series demonstrate a higher propensity to inhibit the processing of amyloid precursor protein compared to Notch, an alternative γ-secretase substrate.